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I'm 35 years old and I have metastatic breast cancer.

Published April 9, 2026 Last Updated July 1, 2026 linkedin verified
At a Glance

I'm 35 years old and I have metastatic breast cancer. Not the most common kind. Not the kind with a clear roadmap. Mine affects less than 1% of all breast cancer cases — a rare subtype called BC-NED: Breast Carcinoma with Neuroendocrine Differentiation. Diagnosed at 32. Already Stage IV. Bone metastases in my spine, pelvis and femur. No visceral disease. ECOG 0. I work, I move, I fight. I've failed two lines of treatment — both stopped due to severe toxicity, not because my body gave up. My lungs survived a necrotizing pneumonia. My liver survived drug-induced injury.

Full intelligence

I'm 35 years old and I have metastatic breast cancer.

Not the most common kind. Not the kind with a clear roadmap.

Mine affects less than 1% of all breast cancer cases — a rare subtype called BC-NED: Breast Carcinoma with Neuroendocrine Differentiation.

Diagnosed at 32. Already Stage IV. Bone metastases in my spine, pelvis and femur.

No visceral disease. ECOG 0. I work, I move, I fight.

I've failed two lines of treatment — both stopped due to severe toxicity, not because my body gave up. My lungs survived a necrotizing pneumonia. My liver survived drug-induced injury.

And I'm still here. Looking for what comes next.

MY TUMOR'S MOLECULAR FINGERPRINT — almost no precedent in the literature:

🔬 FGFR1 ×13 — high-level amplification

🔬 FGF19 ×18 — autocrine loop, FGFR4 activation

🔬 CCND1 ×20 — why CDK4/6 inhibitors failed

🔬 CgA / Synaptophysin 80% — WHO 2022 BC-NED

🔬 4 simultaneous actionable targets. Chemo-naïve. Bone-only.

This combination has not been described as a single molecular portrait in breast cancer literature.

WHAT I'M LOOKING FOR:

✅ WIN MTB international discussion — 4 targets, exactly their population

✅ N-of-1 investigational protocol

✅ Scientific collaboration — full dossier + NGS available. Publishable regardless of outcome.

If you work in FGFR breast cancer, BC-NED, radioligand therapy or N-of-1 oncology — I want to hear from you.

Trying to reach: WIN Consortium in cancer personalized medicine · · Vall d'Hebron Institute of Oncology (VHIO) · Taiho Oncology, Inc. · Razelle Kurzrock · drjaviercortes • Catherine Bresson

Updated molecular results arriving April 14–20, 2026.

I'm not writing this because I've given up.

I'm writing this because I know the science is there.

🔁 If you know someone who should see this — please share.

#BreastCancer #PrecisionOncology #FGFR1 #RareBreastCancer #NofOne #BCNED #CancerResearch #ClinicalTrials

Related hub: Schindler intelligence hub

Original source: https://www.linkedin.com/posts/miriamgonp_breastcancer-precisiononcology-fgfr1-ugcPost-7447828549660753920-wdnr